In vitro bactericidal activity of a carbohydrate polymer with zinc oxide for the treatment of chronic wounds
Abstract
Introduction. Biological adhesives and effective topical therapeutic agents that improve wound healing are urgently required for the treatment of chronic ulcers. A biodegradable adhesive based on a carbohydrate polymer with zinc oxide (CPZO) was shown to possess anti-inflammatory activity and enhance wound healing, but its bactericidal activity was unknown. Aim. To investigate the bactericidal activity of CPZO against bacteria commonly present as infectious agents in chronic wounds.