Relationship between rs4349859 and rs116488202 polymorphisms close to MHC-I region and serum urate levels in patients with gout
Abstract
Gout is the most common inflammatory rheumatic disease and elevated levels of serum urate (SU) are the main cause for its development. Major histocompatibility complex class 1 (MHC-1) plays an important role in the development of multiple inflammatory diseases; however, there is little evidence of its involvement in gout. The present study focused on evaluating the association of the rs4349859 and rs116488202 single nucleotide polymorphisms (SNPs) close to the MHC-1 region in patients with gout.
Tacubaya Hydric District, Ciudad de México, 2022. A Medium-scale Urban Model for Sustainable Water Management in Mexico city
Abstract
As a response to the water crisis in Mexico City, Tacubaya Hydric District proposes a sustainable and decentralized water management system that integrates green and gray infrastructure to valorize urban waters -rainwater, graywater, and blackwater- as a resource rather than waste. © 2023, Pontificia Universidad Catolica de Chile. All rights reserved.
Burnout effect on working mothers in leadership positions during the COVID-19 lockdown
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Abstract
This study aims to understand how the recent COVID-19 pandemic impacted burnout levels among working mothers in leadership positions and how income and work schemes play an important role in their burnout.
Etiology of Primary Cerebellar Intracerebral Hemorrhage Based on Topographic Localization
Abstract
Cerebellar intracerebral hemorrhage (cICH) is often attributed to hypertension or cerebral amyloid angiopathy (CAA). However, deciphering the exact etiology can be challenging. A recent study reported a topographical etiologic relationship with superficial cICH secondary to CAA. We aimed to reexamine this relationship between topography and etiology in a separate cohort of patients and using the most recent Boston criteria version 2.0.