Relationship between rs4349859 and rs116488202 polymorphisms close to MHC-I region and serum urate levels in patients with gout
Abstract
Gout is the most common inflammatory rheumatic disease and elevated levels of serum urate (SU) are the main cause for its development. Major histocompatibility complex class 1 (MHC-1) plays an important role in the development of multiple inflammatory diseases; however, there is little evidence of its involvement in gout. The present study focused on evaluating the association of the rs4349859 and rs116488202 single nucleotide polymorphisms (SNPs) close to the MHC-1 region in patients with gout.
Tacubaya Hydric District, Ciudad de México, 2022. A Medium-scale Urban Model for Sustainable Water Management in Mexico city
Abstract
As a response to the water crisis in Mexico City, Tacubaya Hydric District proposes a sustainable and decentralized water management system that integrates green and gray infrastructure to valorize urban waters -rainwater, graywater, and blackwater- as a resource rather than waste. © 2023, Pontificia Universidad Catolica de Chile. All rights reserved.
Burnout effect on working mothers in leadership positions during the COVID-19 lockdown
- Lee más sobre Burnout effect on working mothers in leadership positions during the COVID-19 lockdown
Abstract
This study aims to understand how the recent COVID-19 pandemic impacted burnout levels among working mothers in leadership positions and how income and work schemes play an important role in their burnout.
Etiology of Primary Cerebellar Intracerebral Hemorrhage Based on Topographic Localization
Abstract
Cerebellar intracerebral hemorrhage (cICH) is often attributed to hypertension or cerebral amyloid angiopathy (CAA). However, deciphering the exact etiology can be challenging. A recent study reported a topographical etiologic relationship with superficial cICH secondary to CAA. We aimed to reexamine this relationship between topography and etiology in a separate cohort of patients and using the most recent Boston criteria version 2.0.
Health-care policies during the COVID-19 pandemic in Mexico: A continuous case of heterogeneous, reactive, and unequal response
Abstract
The pandemic in Mexico underlined pre-existing health-care system inequalities. Within the first six months of the COVID-19 pandemic, 154 health policies across health institutions were found to be uncoordinated and heterogeneous, leading to health inequalities in access and potential health outcomes.
Increased risk of hospitalization and death in Mexican children and adolescents with COVID-19 and comorbidities
Abstract
Although COVID-19 (coronavirus disease 2019) in children is usually mild, they need hospitalization and intensive care in exceptional cases. Adverse outcomes have been observed mainly among children with comorbidities, justifying their vaccination. This study aimed to assess the risk of hospitalization and death in Mexican children and adolescents with COVID-19 and comorbidities.
Epirubicin, cisplatin plus ifosfamide versus standard chemotherapeutic regimens for advanced/unresectable primary thoracic sarcoma
Abstract
Thoracic sarcomas are rare malignancies, with limited data for unresectable/advanced scenarios. Our goal is to provide insights of a three-drug chemotherapy regimen improving patient survival compared to standard regimens.
Agreement between incisional and excisional biopsies for hormone receptors and her2 in breast cancer
Abstract
Breast cancer is the leading cause of cancer mortality in Mexican women.The objective of the study was to identify concordances among core needle biopsy (CNB) and excisional biopsies (EB) regarding diagnosis, hormonal receptors (HR), and human epidermal growth factor receptor 2 (Her2).