
Dr. Alfredo Covarrubias presented scientifically supported findings on the key relationship between intestinal balance and pain mechanisms, opening up new perspectives for comprehensive patient care.
On March 13, 2025, Dr. Alfredo Covarrubias was the guest speaker at our monthly session for march. He addressed a significant and novel topic: the impact of the microbiota on chronic pain. Dr. Covarrubias presented scientifically supported findings on the key relationship between intestinal balance and pain mechanisms, opening new perspectives for the comprehensive care of patients.
During the conference, Dr. Covarrubias explained how intestinal dysbiosis not only triggers but also perpetuates pro-inflammatory states, neuroinflammation, and neurodegeneration, exacerbating chronic pain and other conditions. In contrast, he highlighted that a microbiota in symbiosis promotes neuroprotection and neurogenesis, which could lead to a significant reduction in pain and the prevention of certain pathologies.
One of the most outstanding points of the session was how intestinal bacteria can influence various diseases and affect multiple physiological systems. Through the gut-brain axis, an imbalanced microbiota can promote neuroinflammation and increase the electrical conductance of pain, intensifying its perception.
He emphasized that a healthy biome is not only associated with less pain but also helps block pain receptors due to the presence of beneficial bacteria in adequate amounts. This approach reinforces the importance of multidisciplinary care, where disciplines such as nutrition, psychology, and medicine must work together to optimize the well-being of patients with chronic pain.
Additionally, the session featured an active panel of participants who raised various questions and reflections. Among the most highlighted topics were the influence of nutrition and supplementation on intestinal health, as well as the impact of the microbiota on rheumatological diseases. These questions reflect the growing interest in understanding how intestinal balance can be key in preventing and treating multiple conditions.
The findings presented in this session open new opportunities for innovative and personalized treatments, aiming to improve the quality of life for those suffering from chronic pain. Dr. Covarrubias' next session promises to continue delving into strategies to address this complex condition from a comprehensive perspective.
The Clinical Bioethics and Neuroethics Group Anáhuac (BINCA) has been carrying out academic functions focused on interdisciplinary discussion and research since October 2014. It is affiliated with the Interdisciplinary Clinical Bioethics Project, which includes the faculties of Bioethics, Health Sciences, Education and Humanities, and Psychology at Universidad Anáhuac México.
BINCA consists of students, professors, and researchers from various disciplines and focuses on the study of neuroscience and bioethics from a multidisciplinary perspective.
For more information, visit: https://www.anahuac.mx/mexico/CADEBI/binca
More information:
Bioética Clínica y Neuroética Anáhuac (BINCA)
Dr. María Fernanda Martínez Palomo
maria.martinezp05@anahuac.mx