Enrichment of effector memory T cells in the CD4 and CD8 T cell compartment during chronic graft versus host disease in children

Abstract
During allogeneic Hematopoietic stem cell transplantation (HSCT), frequent pathological scenarios include graft versus host disease (GVHD) and viral infections. We hypothesized if exogenous stimulus as alloantigen and viral antigens might impact on central and effector memory T cells in pediatric recipients.